This is a tip for all you keyboard-junkies out there.
While one advantage to palettes is their ability to dock to one side of the screen and roll up until you need them, sometimes you just want to open them quickly and close them when you're done.
You might know the shortcuts to open a palette (usually Ctrl plus a number, like Ctrl+3 for Tool Palettes), but did you know that there are commands to close palettes as well?
External References: Open = XR (default shortcut); Close = EXTERNALREFERENCESCLOSE
Layer Palette: Open = LA (default shortcut); Close = LAYERCLOSE
Properties Palette: Open = Ctrl+1; Close = PROPERTIESCLOSE
Design Center: Open = Ctrl+2; Close = ADCCLOSE
Tool Palettes: Open = Ctrl+3; Close = TOOLPALETTESCLOSE
Markup Set Manager: Open = Ctrl+7; Close = MARKUPCLOSE
QuickCalc: Open = Ctrl+8; Close = QCCLOSE
Obviously these are a little long for typing in every time, but you can make your own shortcut in the PGP file, and close your palettes with ease.
<edit 07/11/08> Thanks to Vladmir Michl for pointing out other "close" commands. (See comments.)